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3g, etc. new creatures is divided benign and malignant and some between benign and malignant between Customary ovarian cancer refers new creatures ovarian cancer Edit this paragraph classification of diseases classified by organizational learning occurs ovarian tumors are divided into five categories: ① cell carcinoma Occurs when the body cavity of the embryo epithelial tumors such as serous mucinous tumors ② occurs in germ cell tumors Such as mature and immature teratoma immature in some high degree of malignancy ③ occurred in the sex cord-stromal tumors Multi-function with the secretion of hormones such as granulosa cell tumors ④ occurred in the non-specific stromal tumors Such as fibroma leiomyoma These tumors are rare ⑤ metastases From the gastrointestinal tract breast and pelvic organs 克鲁肯贝格's tumor transferred from malignant tumors such as multi-from the gastrointestinal tract to the 克鲁肯贝格's tumor Ovarian cancer is the most serious threat to women's lives is one of the tumor but not easy early detection Early asymptomatic with the tumor increases may have to fall bloating and other minor discomfort Some tumors produce estrogen can cause menstrual disorders Many people own palpable abdominal mass only for medical treatment but this time the tumor has a large mostly late More advanced ovarian cancer ascites abdominal increasing rapidly patients with a sense gas choke bloating loss of appetite weight loss fever There are complications of ovarian cancer tumor torsion rupture and infection which can cause acute abdominal pain fever and even shock acute manifestations Sudden postural changes during pregnancy and childbirth can induce changes in uterine tumors reversed Small ovarian tumors mainly by gynecological examination revealed that the first step in diagnosis is to distinguish between benign and malignant or physiological Smooth surface activity unilateral cysts are benign; physiological cyst is generally not more than 5 cm diameter; bilateral growing fast and irregularly shaped solid or mixed cystic and solid tumors are often malignant should have with other pelvic masses such as uterine fibroids endometriosis genital inflammation and accessories other than tumors By means of X-ray B ultrasound laparoscopic assisted diagnosis The main treatment is surgery cancer patients need to chemotherapy or radiotherapy Advanced cancer should try most of the tumor and then chemotherapy surgery some patients still have hope of cure Regular gynecological examinations for early detection of early treatment Have been identified as new creatures should be early surgery Edit this section risk factors left ovarian cyst Ovarian cancer etiology is unclear Ovarian tumors are classified as follows: 1 germ cell tumors Dysgerminoma endodermal sinus tumor teratoma (mature - substantive cystic; immature single epithelial - stromal ovarian carcinoid neural ectoderm mixed) embryonal carcinoma malignant mixed germ cell tumor multiple embryonal carcinoma (polyembryoma) choriocarcinoma gonadal blastoma 2 non-germ cell tumors Epithelial (serous mucinous) sex cord - stromal (granules support - interstitial mixed) Edit this paragraph pathogenesis 1 pathogenesis "continuous ovulation" cancer theory: Ovarian tumors in early menarche late menopause women have not produced a high incidence but more often childbirth breastfeeding and oral contraceptives for women cancer risk reduction This "continuous ovulation" cancer theory that ovulation ovarian epithelial cell damage caused by repeated injury and repair process trigger cancer Genetic factors: It is the cause of more recent studies one by the majority of cases of autosomal dominant inheritance Nearly 10 years molecular genetic studies have made great progress Narod et al found a hereditary breast - ovarian cancer (HBOC) syndrome specificity of cancer susceptibility gene on chromosome 17 is now known as BRCA1 has recently been identify susceptibility genes BRCA1 another on chromosome 13 These two mutations to make the most of epithelial ovarian cancer can be hereditary form Hereditary ovarian cancer there are three main types: (1) high-risk patients: one familial ovarian cancer syndrome such as a mother or sister who has ovarian cancer I high-risk patients (2) 50% Hazard: Is breast - ovarian cancer syndrome mother or sister has one or two cancer patients I suffer from the risk of ovarian cancer is 50% (3) is a family history of cancer: risk of ovarian cancer endometrial cancer breast cancer and colorectal cancer risk may increase 2 Pathology (1) histological classification (Table 1): (2) histological grade: Broder determined by the histological undifferentiated cells accounted for 0% to 25% of G1; undifferentiated cells accounted for 25% ~ 50% of G2; undifferentiated cells> 50% of the G3 [1] The risk factors of ovarian cancer is unclear but the environment and endocrine effects in ovarian cancer risk factors in the most attention Epidemiology and etiology according to their survey its risk factors and risk groups are: ⑴ Environmental factors: industrial countries and the upper classes of society women with ovarian cancer incidence may be related to high cholesterol diet related Furthermore ionizing radiation and asbestos talc affect oocyte increases the chance of ovarian tumors induced by smoking and vitamins A C E may also be lack of pathogenesis ⑵ endocrine factors: ovarian tumors occurred in nulliparous women or fertility pregnancy on ovarian tumors seems antagonism that caused ovulation day repeated ovarian surface epithelial cells and ovarian tumorigenesis damaged In addition breast cancer endometrial cancer ovarian cancer and more complicated these three diseases are estrogen-dependent ⑶ genetic and familial factors: approximately 30% -50% of patients with ovarian cancer in relatives of cancer patients Edit this paragraph chromosomal changes over a long period of time due to the preparation of solid tumors chromosome technically difficult so for ovarian cancer awareness chromosomal changes slow progress In recent years with the development of methodology information in this regard have more accumulation Chromosomal changes benign ovarian tumors was not significant the most common are trisomy 12 Malignant ovarian tumors changes in chromosome number nearly diploid type of tumor prognosis Malignant ovarian tumors chromosome structural change is more complex the following table lists the ovarian cancer often involved chromosomes Although individual chromosomal rearrangement frequency and length of the chromosome may be relevant but some chromosomes seem more often affected than others For example 3 and 6 of chromosome rearrangements quite common and 24 and 5 but rare chromosome abnormalities On chromosome 3 and 6 the common abnormalities deletions and rearrangements breaking point in the 1p3-4 1p36 3p14-21 6p15-21 Other more common rearrangement occurs in 7p 10q 11p 14q and 19q Also reported marked chromosomes including isochromosome i (4p) i (5p) i (6p) and i (12p) Especially i (12P) especially noteworthy because also found in male germ cell tumors From some of the patient's follow-up observation shows that in the process of tumor development chromosomal change continues Cytogenetic studies showed the loss of certain chromosomal zone and other zones of amplification suggesting that these parts should be used as molecular studies goals In borderline cystadenocarcinoma after 7-12 days after culture preparation chromosome analysis showed trisomy 10 may be specific chromosomal changes early [2] studied the number of cases found in the number of cases of abnormal chromosomal abnormalities 22181672317137112019135691112981 p 3p 6q 78 p 10q 126616 q44421p 6q Edit this paragraph clinical symptoms ovarian cystadenoma a the clinical manifestations of benign ovarian tumors: tumors grow slowly and often asymptomatic early often found incidentally in Cervical With the increased tumor appears bloating abdominal touched from the patient's own tumor if the tumor is large and filled pelvic compression can produce symptoms such as frequent urination constipation Abdominal examination outline clearly palpable tumor Gynecological when touched in the womb of one or both of cystic or solid mass smooth surface and activities not connected with the uterus Generally benign no pain only in the event of complications such as torsion rupture or secondary infection caused by abdominal pain Second the clinical manifestations of malignant ovarian tumors: Early no more symptoms such symptoms are often at a late stage Short-term rapid growth of the tumor abdominal distension ascites and compression symptoms or the occurrence of the surrounding tissue infiltration functioning tumors can produce the corresponding estrogen or androgen excess symptoms Advanced patient weakness weight loss anemia cachexia and other phenomena Women search touched tumors were solid bilateral uneven surface fixed and uterus rectum palpable nodules sometimes axillary supraclavicular palpable enlarged lymph nodes Both benign and malignant complications can occur such as tumor torsion tumor rupture infection malignant transformation Adolescent and pediatric clinical manifestations of ovarian tumor characteristics 1 the incidence of ovarian tumors in children although lower but soon after the occurrence of tumor growth malignant than in adults Start obvious symptoms early diagnosis difficult if not treated early or not complete then the prognosis is poor 2 embryonic ovary in the abdominal cavity pelvic fell to adolescence Pediatric pelvis is narrow can not accommodate large lumps so children suffering from ovarian cancer often with abdominal mass as the main symptoms 3 abdominal pain is a common symptom [3] mostly Cullen or persistent lower abdominal pain due to tumor stimulation peritoneum abdominal bleeding caused by compression of the surrounding tissue or adhesions Sometimes cancer can also be worn on their own cause abdominal pain 4 pediatric pelvis smaller tumors quickly rose to the abdominal cavity Ovarian cancer rises tumor Umatilla long while hyperactivity in children cystic mass are more likely to reverse causing acute abdominal pain tumor increases tenderness and peritoneal irritation Torsion of ovarian tumors in children the incidence was significantly higher than in adults 5 there are endocrine function of ovarian tumors such as sex cord stromal tumors of granulosa cell tumor theca cell tumor tubular ring sex cord stromal tumors primary choriocarcinoma etc, Tan Jingming kiosk that under the old Hall.
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